- Title
- Crystallographic Study of a Novel Subnanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 Reverse Transcriptase
- Creators
- Matthew D CULLEN - Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences, and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United StatesWilliam C HO - Department of Chemistry and Chemical Biology, Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, United StatesMark CUSHMAN - Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmaceutical Sciences, and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United StatesJoseph D BAUMAN - Department of Chemistry and Chemical Biology, Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, United StatesKalyan DAS - Department of Chemistry and Chemical Biology, Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, United StatesEddy AMOLD - Department of Chemistry and Chemical Biology, Center for Advanced Biotechnology and Medicine, Rutgers University, 679 Hoes Lane West, Piscataway, New Jersey 08854, United StatesTracy L HARTMAN - ImQuest Biosciences, Inc., 7340 Executive Way, Suite R, Frederick, Maryland 21704, United StatesKaren M WATSON - ImQuest Biosciences, Inc., 7340 Executive Way, Suite R, Frederick, Maryland 21704, United StatesRobert W BUCKHEIT - ImQuest Biosciences, Inc., 7340 Executive Way, Suite R, Frederick, Maryland 21704, United StatesChristophe PANNECOUQUE - Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, BelgiumErik DE CLEREQ - Rega Institute for Medical Research, Katholieke Universiteit Leuven, 3000 Leuven, Belgium
- Publication Details
- Journal of medicinal chemistry, Vol.52(20), pp.6467-6473
- Date published
- 2009
- Publisher
- American Chemical Society
- Academic Unit
- Center for Advanced Biotechnology and Medicine
- Language
- English
- Resource Type
- Journal article
- Identifiers
- 991031654705804646
Journal article
Crystallographic Study of a Novel Subnanomolar Inhibitor Provides Insight on the Binding Interactions of Alkenyldiarylmethanes with Human Immunodeficiency Virus-1 Reverse Transcriptase
Journal of medicinal chemistry, Vol.52(20), pp.6467-6473
2009
PMID: 19775161
Metrics
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