Abstract
Background: Squamous carcinoma-in-situ(CIS) within a benign cystic teratoma is exceptionally rare, particularly in the absence of an adjacent invasive squamous component. Most of the few reported cases of CIS without invasive carcinoma occur in postmenopausal women, and are usually incidental histopathologic findings. Case: We present a case of CIS in a benign cystic teratoma, which preceded invasive squamous cell carcinoma in the contralateral ovary, and review the literature. Conclusions: In the absence of invasion, excision of the ovary with CIS appears to be adequate therapy. If CIS is detected histopathologically, a search for invasive elements should be undertaken.