Abstract
In the last retrospective on regional input-output analysis, Hewings and Jensen (1988) set out a set of emerging challenges. This paper generally examines how those challenges have been met in the intervening 25 years (plus some). A feature of this endeavor is to help young scholars identify research directions. In this vein, along the way I point out avenues that could be pursued. I conclude by identifying topics in input-output analysis that are currently hot and those that are not.