Abstract
Phospholipids are essential molecules that contribute to the structural definition of the cell. They also play a role as signaling molecules that participate in the regulation of cellular processes. The yeast Saccharomyces cerevisiae has been used as a model system to study phospholipid synthesis and its regulation in eukaryotes. Molecular, genetic, and biochemical studies have shown that phospholipid synthesis is regulated in a coordinated fashion. The mechanisms that govern this regulation mediate the messenger RNA and protein levels of the biosynthetic enzymes, as well as their activity and localization.