Abstract
Two recent crystal structures of the tetrameric pterin-4
α-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF-1 (DCoH) protein provide fresh insights into how this multifunctional enzyme/transcriptional coactivator works.
- Title
- PCD/DCoH: more than a second molecular saddle
- Creators
- Joseph L Kim - Joseph L Kim, Vertex Pharmaceuticals, Inc., 40 Allston Street, Cambridge, MA 02139-4211, USAStephen K Burley - Stephen K Burley, Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA
- Publication Details
- Structure, Vol.3(6), pp.531-534
- Date published
- 1995
- Publisher
- Elsevier Inc
- Academic Unit
- Chemistry and Chemical Biology (SAS); Institute for Quantitative Biomedicine
- Language
- English
- Resource Type
- Review
- Identifiers
- 991031666083704646