2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Hao Tang; Suresh Venkatesh; Zhongtian Lin; Xuyang Lu; Hooman Saeidi; Gulam M Rather; Joseph R Bertino; Chen-Yong Lin; Mehdi Javanmard; Kaushik Sengupta

doi:10.1109/CICC.2019.8780363

Conference proceeding

2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate

Hao Tang, Suresh Venkatesh, Zhongtian Lin, Xuyang Lu, Hooman Saeidi, Gulam M Rather, Joseph R Bertino, Chen-Yong Lin, Mehdi Javanmard and Kaushik Sengupta

2019 IEEE Custom Integrated Circuits Conference (CICC), Vol.2019-, pp.1-4

04/2019

DOI: https://doi.org/10.1109/CICC.2019.8780363

Abstract

Cancer

Correlation

Frequency measurement

Oscillators

Sensor arrays

Temperature measurement

Two dimensional displays

In this article, we present a 2D oscillator array-based magnetic sensor CMOS IC for flow cytometry. The CMOS IC packaged with a microfluidic channel eliminates the need for hydro-focusing by allowing uninhibited flow over the 2D chip surface. The chip exploits multi-site detection capability allowing simultaneously high flow rate for trace cell detection, reduced false positives, and real-time cell tracking. We demonstrate these functionalities with a 7 \times 7 array in 65-nm CMOS with lymphoma cancer cells.

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Details

Title: 2D Magnetic Sensor Array for Real-time Cell Tracking and Multi-site Detection with Increased Robustness and Flow-rate
Creators: Hao Tang - Department of Electrical Engineering, Princeton University
Suresh Venkatesh - Department of Electrical Engineering, Princeton University
Zhongtian Lin - Department of Electrical and Computer Engineering, Rutgers University
Xuyang Lu - Department of Electrical Engineering, Princeton University
Hooman Saeidi - Department of Electrical Engineering, Princeton University
Gulam M Rather - Rutgers Cancer Institute of New Jersey
Joseph R Bertino - Rutgers Cancer Institute of New Jersey
Chen-Yong Lin - Department of Oncology, Georgetown University
Mehdi Javanmard - Department of Electrical and Computer Engineering, Rutgers University
Kaushik Sengupta - Department of Electrical Engineering, Princeton University
Publication Details: 2019 IEEE Custom Integrated Circuits Conference (CICC), Vol.2019-, pp.1-4
Date published: 04/2019
Publisher: IEEE
Academic Unit: Electrical and Computer Engineering (SOE); Bertino Office
Language: English
Resource Type: Conference proceeding
Identifiers: 991031665791204646