A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

Matilde Murga; Samuel Bunting; Maria F Montana; Rebeca Soria; Francisca Mulero; Marta Canamero; Youngsoo Lee; Peter J Mckinnon; Andre Nussenzweig; Oscar FERNANDEZ-CAPETILLO

doi:10.1038/ng.420

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A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

Journal article

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Peer reviewed

A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

Matilde Murga, Samuel Bunting, Maria F Montana, Rebeca Soria, Francisca Mulero, Marta Canamero, Youngsoo Lee, Peter J Mckinnon, Andre Nussenzweig and Oscar FERNANDEZ-CAPETILLO

Nature genetics, Vol.41(8), pp.891-898

2009

DOI: https://doi.org/10.1038/ng.420

PMID: 19620979

Abstract

Biological and medical sciences

Fundamental and applied biological sciences. Psychology

Genetics of eukaryotes. Biological and molecular evolution

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Title: A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Creators: Matilde Murga - Genomic Instability Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
Samuel Bunting - Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States
Maria F Montana - Genomic Instability Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
Rebeca Soria - Genomic Instability Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
Francisca Mulero - Molecular Imaging Unit, CNIO, Madrid, Spain
Marta Canamero - Comparative Pathology Unit, CNIO, Madrid, Spain
Youngsoo Lee - Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Peter J Mckinnon - Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States
Andre Nussenzweig - Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States
Oscar FERNANDEZ-CAPETILLO - Genomic Instability Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
Publication Details: Nature genetics, Vol.41(8), pp.891-898
Date published: 2009
Publisher: Nature Publishing Group
Academic Unit: Molecular Biology and Biochemistry (SAS)
Language: English
Resource Type: Journal article
Identifiers: 991031666215604646