Sign in
Back
An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones
Journal article   Peer reviewed

An efficient, asymmetric organocatalyst-mediated conjugate addition of nitroalkanes to unsaturated cyclic and acyclic ketones

Claire E T Mitchell, Stacey E Brenner, Jorge García-Fortanet and Steven V Ley
Organic & biomolecular chemistry, Vol.4(10), pp.2039-249
05/21/2006
DOI: https://doi.org/10.1039/b601877g
PMID: 16688349

Abstract

Catalysis Ketones - chemistry Nitro Compounds - chemistry
5-Pyrrolidin-2-yltetrazole is a versatile organocatalyst for the asymmetric conjugate addition of nitroalkanes to enones. Using this catalyst, this transformation requires short reaction times, tolerates a broad substrate scope, and possibly proceeds via generation of an iminium species.

Metrics

14 Record Views
84 Times Cited - Web of Science

Details