Abstract
A quantitative ultraviolet detection method for the determination of urinary metabolites is described using capillary zone electrophoresis. The determination of these metabolites is simple, fast. reproducible and utilizes very small amounts of sample. This method is linear between 1.0 × 10
−4
and 1.0 × 10
−2
M for creatinine and between 1.0 × 10
−1
and 1.0 M for urea. The ultraviolet method shows detection limits for creatinine in the picogram (femtomol) range, and for urea in the nanogram (picomol) range.