- Title
- Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives : A new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains
- Creators
- Daniel M HIMMEL - Center for Advanced Biotechnology and Medicine (CABM) and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United StatesKalyan DAS - Center for Advanced Biotechnology and Medicine (CABM) and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United StatesChristophe MEYER - Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP315, Val de Reuil, FranceKoen ANDRIES - Virology Drug Discovery, Johnson & Johnson Pharmaceutical Research and Development, Tumhoutseweg 30, 2340 Beerse, BelgiumCHI HUNG NGUYEN - Laboratoire de Pharmacochimie, Section de Recherche, UMR 176 CNRS-Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay, FranceDavid S GRIERSON - Laboratoire de Pharmacochimie, Section de Recherche, UMR 176 CNRS-Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay, FranceEddy ARNOLD - Center for Advanced Biotechnology and Medicine (CABM) and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United StatesArthur D CLARK - Center for Advanced Biotechnology and Medicine (CABM) and Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, New Jersey 08854, United StatesStephen H HUGHES - HIV Drug Resistance Program, NCI-Frederick Cancer Research and Development Center, Building 539, Frederick, Maryland 21702, United StatesAbdellah BENJAHAD - Laboratoire de Pharmacochimie, Section de Recherche, UMR 176 CNRS-Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay, FranceSaid OUMOUCH - Laboratoire de Pharmacochimie, Section de Recherche, UMR 176 CNRS-Institut Curie, Batiment 110, Centre Universitaire, 91405 Orsay, FranceJérome GUILLEMONT - Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP315, Val de Reuil, FranceSophie COUPA - Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP315, Val de Reuil, FranceAlain PONCELET - Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP315, Val de Reuil, FranceImre CSOKA - Medicinal Chemistry Department, Johnson & Johnson Pharmaceutical Research and Development, Campus de Maigremont BP315, Val de Reuil, France
- Publication Details
- Journal of medicinal chemistry, Vol.48(24), pp.7582-7591
- Date published
- 2005
- Publisher
- American Chemical Society
- Academic Unit
- Center for Advanced Biotechnology and Medicine
- Language
- English
- Resource Type
- Journal article
- Identifiers
- 991031654675604646
Journal article
Crystal structures for HIV-1 reverse transcriptase in complexes with three pyridinone derivatives : A new class of non-nucleoside inhibitors effective against a broad range of drug-resistant strains
Journal of medicinal chemistry, Vol.48(24), pp.7582-7591
2005
PMID: 16302798
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