Enterovirus A71 Vaccines

Mei-Ling Li; Shin-Ru Shih; Blanton S Tolbert; Gary Brewer

doi:10.3390/vaccines9030199

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Journal article

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Peer reviewed

Enterovirus A71 Vaccines

Mei-Ling Li, Shin-Ru Shih, Blanton S Tolbert and Gary Brewer

Vaccines (Basel), Vol.9(3), pp.1-10

02/27/2021

DOI: https://doi.org/10.3390/vaccines9030199

PMID: 33673595

Abstract

vaccine

Enterovirus A71

Sinovac

foot and mouth disease (HFMD)

hand

Enterovirus A71 (EV-A71) is a major causative agent of hand, foot, and mouth disease (HFMD) and herpangina. Moreover, EV-A71 infection can lead to neurological complications and death. Vaccination is the most efficient way to control virus infection. There are currently three inactivated, whole EV-A71 vaccines licensed by the China NMPA (National Medical Products Administration). Several other types of vaccines, such as virus-like particles and recombinant VP1 (capsid protein), are also under development. In this review, we discuss recent advances in the development of EV-A71 vaccines.

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Title: Enterovirus A71 Vaccines
Creators: Mei-Ling Li - Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
Shin-Ru Shih - Research Center for Chinese Herbal Medicine, Research Center for Food and Cosmetic Safety, and Graduate Institute of Health Industry Technology, College of Human Ecology, Chang Gung University of Science and Technology, Taoyuan 333, Taiwan
Blanton S Tolbert - Department of Chemistry, Case Western Reserve University, Cleveland, OH 44106, USA
Gary Brewer - Department of Biochemistry and Molecular Biology, Rutgers Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA
Publication Details: Vaccines (Basel), Vol.9(3), pp.1-10
Date published: 02/27/2021
Grant note: R01 GM126833 to GB and BST / NIH HHS MOST 108-3017-F-182-001 to SRS / The Ministry of Education in Taiwan and the Ministry of Science and Technology, Taiwan
Academic Unit: Biochemistry and Molecular Biology (RWJMS)
Language: English
Resource Type: Journal article
Identifiers: 991031665773404646