Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses

Andre A Teixeira; Serena Marchiò; Emmanuel Dias‐Neto; Diana N Nunes; Israel T da Silva; Bryce Chackerian; Marc Barry; Richard C Lauer; Ricardo J Giordano; Richard L Sidman; Cosette M Wheeler; Webster K Cavenee; Renata Pasqualini; Wadih Arap

doi:10.15252/emmm.201708072

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Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses

Journal article

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Peer reviewed

Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses

Andre A Teixeira, Serena Marchiò, Emmanuel Dias‐Neto, Diana N Nunes, Israel T da Silva, Bryce Chackerian, Marc Barry, Richard C Lauer, Ricardo J Giordano, Richard L Sidman, …

EMBO molecular medicine, Vol.9(10), pp.1327-1330

10/2017

DOI: https://doi.org/10.15252/emmm.201708072

PMCID: PMC5623838

PMID: 28751581

Abstract

Urogenital System

Opinion

Microbiology, Virology & Host Pathogen Interaction

Cancer

The hypothesis is discussed that prostate cancer marker lnc RNA PCA 3 was introduced into the human genome by an oncogenic virus, and that viral infection‐related mechanisms might underlie its overexpression and prostate cancer initiation and/or progression.

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Title: Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses
Creators: Andre A Teixeira - University of New Mexico Comprehensive Cancer Center
Serena Marchiò - University of New Mexico Comprehensive Cancer Center
Emmanuel Dias‐Neto - A.C.Camargo Cancer Center
Diana N Nunes - A.C.Camargo Cancer Center
Israel T da Silva - A.C.Camargo Cancer Center
Bryce Chackerian - University of New Mexico
Marc Barry - University of New Mexico Comprehensive Cancer Center
Richard C Lauer - University of New Mexico Comprehensive Cancer Center
Ricardo J Giordano - University of São Paulo
Richard L Sidman - Harvard Medical School
Cosette M Wheeler - University of New Mexico Comprehensive Cancer Center
Webster K Cavenee - University of California‐San Diego
Renata Pasqualini - University of New Mexico Comprehensive Cancer Center
Wadih Arap - University of New Mexico Comprehensive Cancer Center
Publication Details: EMBO molecular medicine, Vol.9(10), pp.1327-1330
Date published: 10/2017
Publisher: John Wiley and Sons Inc
Grant note: 2016/06069‐0 / FAPESP UNM Cancer Center Support Grant P30 CA118100 / Foundation for the National Institutes of Health (FNIH)
Academic Unit: Radiation Oncology; Cancer Institute of New Jersey at University Hospital
Language: English
Resource Type: Journal article
Identifiers: 991031654033704646