Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast

Naomi A. Miller; Judith-Anne W. Chapman; William A. Christens-Barry; Yuejiao Fu; Yan Yuan; H. Lavina Lickley; David E. Axelrod

doi:10.7282/T337773B

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Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast

Journal article

Open access

Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast

Naomi A. Miller, Judith-Anne W. Chapman, William A. Christens-Barry, Yuejiao Fu, Yan Yuan, H. Lavina Lickley and David E. Axelrod

Cancer Informatics, Vol.2010(9), pp.209-216

2010

DOI:

https://doi.org/10.7282/T337773B

Abstract

Breast ductal carcinoma in situ

Heterogeneity

Nuclear grade

Image analysis

Breast--Cancer

Nuclei in ducts visually described as having the same nuclear grade had significantly different subvisual digital image features. These subvisual differences may be considered additional manifestations of heterogeneity over and above differences that can be observed microscopically. This heterogeneity may explain the inconsistency of nuclear grading as a prognostic factor.

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Title: Subtitle: Heterogeneity Between Ducts of the Same Nuclear Grade Involved by Duct Carcinoma In Situ (DCIS) of the Breast
Creators: Naomi A. Miller (Author) - University Health Network (Toronto, Ont.)
Judith-Anne W. Chapman (Author) - Queens University (Kingston, Ont.)
William A. Christens-Barry (Author) - Equipoise Imaging LLC
Yuejiao Fu (Author) - York University
Yan Yuan (Author) - Alberta Health Services
H. Lavina Lickley (Author) - Henrietta Banting Breast Centre, Women's College Hospital
David E. Axelrod (Author) - Genetics, Rutgers University
Publication Details: Cancer Informatics, Vol.2010(9), pp.209-216
Date published: 2010
Publisher: Libertas Academica
Number of pages: 8 p.
Grant note: National Institutes of Health (U.S.) - U56 CA113004 ; Canadian Cancer Society ; New Jersey Commission for Cancer Research - 1076-CCR-S0
Academic Unit: School of Arts and Sciences; Genetics (SAS)
Language: English
Resource Type: Journal article
Comment: The published version version of this article is available at: http://www.la-press.com/article.php?article_id=2250
Identifiers: 991031549985504646