Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Jeffrey T BAGDANOFF; Michael S DONOVIEL; Simon D. P BAUGH; Michael GARDYAN; Kristen M TERRANOVA; Joseph BARBOSA; Jack YAN; Mark BEDNARZ; Suman LAYEK; Lawrence F COURTNEY; Jerry TAYLOR; Ann Marie DIGEORGE-FOUSHEE; Amr NOURALDEEN; Suma GOPINATHAN; Debra BRUCE; Traci SMITH; Liam MORAN; Emily O'NEILL; Jeff KRAMER; ZHONG LAI; S. David KIMBALL; QINGYUN LIU; WEIMEI SUN; James TARVER; Sean YU; Jonathan SWAFFIELD; Alan WILSON; Alan MAIN; Kenneth G CARSON; Tamas ORAVECZ; David J AUGERI; QINGHONG FU; Marianne CARLSEN; Theodore C JESSOP; HAIMING ZHANG; Jill HAZELWOOD; Huy NGUYEN

doi:10.1021/jm900278w

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Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Journal article

Peer reviewed

Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders

Jeffrey T BAGDANOFF, Michael S DONOVIEL, Simon D. P BAUGH, Michael GARDYAN, Kristen M TERRANOVA, Joseph BARBOSA, Jack YAN, Mark BEDNARZ, Suman LAYEK, Lawrence F COURTNEY, …

Journal of medicinal chemistry, Vol.52(13), pp.3941-3953

2009

DOI: https://doi.org/10.1021/jm900278w

PMID: 19489538

Abstract

Biological and medical sciences

Medical sciences

Immunomodulators

Pharmacology. Drug treatments

Bones, joints and connective tissue. Antiinflammatory agents

Metrics

11 Record Views

65 Times Cited - Web of Science

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Details

Title: Inhibition of Sphingosine-1-Phosphate Lyase for the Treatment of Autoimmune Disorders
Creators: Jeffrey T BAGDANOFF - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Michael S DONOVIEL - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Simon D. P BAUGH - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Michael GARDYAN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Kristen M TERRANOVA - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Joseph BARBOSA - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Jack YAN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Mark BEDNARZ - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Suman LAYEK - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Lawrence F COURTNEY - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Jerry TAYLOR - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Ann Marie DIGEORGE-FOUSHEE - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Amr NOURALDEEN - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Suma GOPINATHAN - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Debra BRUCE - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Traci SMITH - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Liam MORAN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Emily O'NEILL - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Jeff KRAMER - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
ZHONG LAI - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
S. David KIMBALL - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
QINGYUN LIU - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
WEIMEI SUN - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
James TARVER - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Sean YU - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Jonathan SWAFFIELD - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Alan WILSON - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Alan MAIN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Kenneth G CARSON - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Tamas ORAVECZ - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
David J AUGERI - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
QINGHONG FU - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Marianne CARLSEN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Theodore C JESSOP - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
HAIMING ZHANG - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Jill HAZELWOOD - Lexicon Pharmaceuticals, 8800 Technology Forest Place, The Woodlands, Texas 77381, United States
Huy NGUYEN - Lexicon Pharmaceuticals, 350 Carter Road, Princeton, New Jersey, 08540, United States
Publication Details: Journal of medicinal chemistry, Vol.52(13), pp.3941-3953
Date published: 2009
Publisher: American Chemical Society
Academic Unit: Medicinal Chemistry (EMSOP); Rutgers Translational Sciences; Office of Research and Economic Development
Language: English
Resource Type: Journal article
Identifiers: 991031654475704646