Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model

Prashant Dogra; Javier Ruiz-Ramírez; Kavya Sinha; Joseph D Butner; Maria J Peláez; Manmeet Rawat; Venkata K Yellepeddi; Renata Pasqualini; Wadih Arap; H. Dirk Sostman; Vittorio Cristini; Zhihui Wang

doi:10.1021/acsptsci.0c00183

Journal article

Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model

Prashant Dogra, Javier Ruiz-Ramírez, Kavya Sinha, Joseph D Butner, Maria J Peláez, Manmeet Rawat, Venkata K Yellepeddi, Renata Pasqualini, Wadih Arap, H. Dirk Sostman, …

ACS pharmacology & translational science, Vol.4(1), pp.248-265

02/12/2021

DOI: https://doi.org/10.1021/acsptsci.0c00183

PMID: 33615177

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Title: Innate Immunity Plays a Key Role in Controlling Viral Load in COVID-19: Mechanistic Insights from a Whole-Body Infection Dynamics Model
Creators: Prashant Dogra - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States
Javier Ruiz-Ramírez - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States
Kavya Sinha - DeBakey Heart and Vascular Center, Houston Methodist Hospital, Houston, Texas 77030, United States
Joseph D Butner - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States
Maria J Peláez - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States
Manmeet Rawat - Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, United States
Venkata K Yellepeddi - Division of Clinical Pharmacology, Department of Pediatrics, School of Medicine, University of Utah, Salt Lake City, Utah 84132, United States, Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of Utah, Salt Lake City, Utah 84112, United States
Renata Pasqualini - Rutgers Cancer Institute of New Jersey, Newark, New Jersey 07101, United States, Department of Radiation Oncology, Division of Cancer Biology, Rutgers New Jersey Medical School, Newark, New Jersey 07103, United States
Wadih Arap - Rutgers Cancer Institute of New Jersey, Newark, New Jersey 07101, United States, Department of Medicine, Division of Hematology/Oncology, Rutgers New Jersey Medical School, Newark, New Jersey 07103, United States
H. Dirk Sostman - Weill Cornell Medicine, New York, New York 10065, United States, Houston Methodist Research Institute, Houston, Texas 77030, United States, Houston Methodist Academic Institute, Houston, Texas 77030, United States
Vittorio Cristini - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States, Weill Cornell Medicine, New York, New York 10065, United States
Zhihui Wang - Mathematics in Medicine Program, Houston Methodist Research Institute, Houston, Texas 77030, United States, Weill Cornell Medicine, New York, New York 10065, United States
Publication Details: ACS pharmacology & translational science, Vol.4(1), pp.248-265
Date published: 02/12/2021
Academic Unit: Radiation Oncology; Cancer Institute of New Jersey at University Hospital
Language: English
Resource Type: Journal article
Identifiers: 991031654674104646