Abstract
A new bifunctional organocatalyst with a novel structural and functional motif has been developed. This bifunctional sulfonamide organocatalyst was used in the conjugate addition of 1,3-dicarbonyl compounds (
13) to β-nitrostyrenes (
12). Yields up to 91% and enantiomeric excesses up to 79% were obtained in this reaction. This catalyst activates both
13 via its basic moiety and
12 through hydrogen bonding.
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