Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis

Kelly D Daughtry; Hua Huang; Vladimir Malashkevich; Yury Patskovsky; Weifeng Liu; Udupi Ramagopal; J. Michael Sauder; Stephen K Burley; Steven C Almo; Debra Dunaway-Mariano; Karen N Allen; Brookhaven National Laboratory (BNL)

doi:10.1021/bi400659k

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Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis

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Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis

Kelly D Daughtry, Hua Huang, Vladimir Malashkevich, Yury Patskovsky, Weifeng Liu, Udupi Ramagopal, J. Michael Sauder, Stephen K Burley, Steven C Almo, Debra Dunaway-Mariano, …

Biochemistry (Easton), Vol.52(32), pp.5372-5386

08/13/2013

DOI: https://doi.org/10.1021/bi400659k

PMCID: PMC3966652

PMID: 23848398

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Title: Structural Basis for the Divergence of Substrate Specificity and Biological Function within HAD Phosphatases in Lipopolysaccharide and Sialic Acid Biosynthesis
Creators: Kelly D Daughtry - Department of Physiology and Biophysics, Boston University School of Medicine, Boston, Massachusetts 02118-2394, United States
Hua Huang - Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico 87131-0001, United States
Vladimir Malashkevich - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, United States
Yury Patskovsky - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, United States
Weifeng Liu - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, United States
Udupi Ramagopal - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, United States
J. Michael Sauder - Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, California 92121, United States
Stephen K Burley - Lilly Biotechnology Center, 10300 Campus Point Drive, San Diego, California 92121, United States
Steven C Almo - Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461, United States
Debra Dunaway-Mariano - Department of Chemistry and Chemical Biology, University of New Mexico, Albuquerque, New Mexico 87131-0001, United States
Karen N Allen - Department of Chemistry, Boston University, Boston, Massachusetts 02215-2521, United States
Brookhaven National Laboratory (BNL)
Publication Details: Biochemistry (Easton), Vol.52(32), pp.5372-5386
Date published: 08/13/2013
Academic Unit: Chemistry and Chemical Biology (SAS); Institute for Quantitative Biomedicine
Language: English
Resource Type: Journal article
Identifiers: 991031665649004646