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High-density mapping of the MHC identifies a shared role for HLA-DRB1∗01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
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High-density mapping of the MHC identifies a shared role for HLA-DRB1∗01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

Philippe Goyette, Gabrielle Boucher, Dermot Mallon, Eva Ellinghaus, Luke Jostins, Hailiang Huang, Stephan Ripke, Elena S Gusareva, Vito Annese, Stephen L Hauser, …
Nature genetics, Vol.47(2), pp.172-179
Nature Publishing Group
01/01/2015
PMID: 25559196

Abstract

Alleles; Chromosome Mapping; Colitis, Ulcerative; Crohn Disease; Genetic Linkage; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Genotyping Techniques; HLA-DRB1 Chains; Heterozygote; Humans; Inflammatory Bowel Diseases; Major Histocompatibility Complex; Phenotype; Polymorphism, Single Nucleotide; Genetics
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https://doi.org/10.1038/ng.3176View
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