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Antibacterial agents: salinamide derivatives
Patent   Open access

Antibacterial agents: salinamide derivatives

Richard H. Ebright, Yon W. Ebright, Yu Feng and David Degen
11/07/2017

Abstract

CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES Metallurgy Organic Chemistry Peptides
The invention provides compounds of formula (I): and salts thereof, wherein X and Y have any of the values defined herein. The compounds inhibit bacterial RNA polymerase, inhibit bacterial growth, and have applications in, analysis of RNA polymerase structure and function, control of bacterial gene expression, control of bacterial growth, antibacterial chemistry, antibacterial therapy, and drug discovery.
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